For the selected entities, interaction graphs are generated from different data sources and dynamically presented. Moreover, genes and miRNAs can jointly be provided to the tool in the bidirectional search mode. Users input in the unidirectional search mode either a single gene, gene set or gene pathway, alternatively a single miRNA, a set of miRNAs or an miRNA pathway. With miRTargetLink 2.0, we develop an all-in-one solution for human, mouse and rat miRNA networks. A comprehensive analysis should be central to present adequate answers to complex biological questions. Especially for researchers without computational experience, the integration of different data sources, selection of the right parameters and concise visualization can be demanding. Which genes, gene sets or pathways are regulated by certain miRNAs? Which miRNAs regulate a particular target gene or target pathway in a certain physiological context? Answering such common research questions can be time consuming and labor intensive.
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